The clinical and histopathological co-relation of psoriasiform dermatoses.

Background: Psoriasiform dermatoses is a common presentation of a wide spectrum of underlying diseases from a relatively harmless disease like chronic dermatitis to a detrimental disease like mycosis fungoides. Psoriasiform reaction pattern is a commonly encountered denominator in a wide variety of unrelated disorders. They include several unrelated disorders of the integument, which either in the beginning or in the course of progression/resolution, exhibit lesions resembling psoriasis. Aims: This study was designed and conducted to enlist clinical parameters, histopathology and clinicohistopathological co-relation of psoriasiform disorders. Methodology: 100 cases of psoriasiform dermatoses over a period of two years were studied. Their history, age, sex as well as morphology, distribution and histopathology of skin lesions were analysed. Results: Psoriasis is the commonest of all psoriasiform dermatoses (31%) followed by lichen planus (23%),lichen nitidus(9%), pitryasis rosea (7%) , seborrheic dermatitis (6%). The remaining dermatoses like lichenoid drug eruptions ,parapsoriasis , Reiter’s disease , mycosis fungoides , pitryriasis rubra pilaris and lichen striatus, lichen simplex chronic etc were uncommon. There was a slight male preponderance. (M: F: 1.3:1). Lesions were more common in limbs. There was a wide age variation for example lichen striatus was seen in 5 year male and mycosis fungoides in a 69 year old male. A good clinicopathological co-relation filled up the lacunae of both, the clinical approach as well as that of histopathology and helped in pinpointing the diagnosis (62 cases). In 10 cases, there was no co-relation between clinical and histopathological diagnosis. Conclusion: As the morbidity of these disorders ranges from a trifling affliction to a life threat, thorough clinico-pathological co-relation and prompt institution of specific treatment results in a better prognosis.

A cytological and histomorphological case study of an uncommon breast carcinoma: Invasive papillary type.

Pure papillary carcinoma of the breast is a rare tumour affecting elderly postmenopausal women. We report one case in a relatively younger woman presenting with a clinically benign breast lump.The tumour showed extensive apocrine metaplasia. The ease with which abundant material with highly cellular papillary clumps is obtained on fine needle aspirate should be an important consideration favouring papillary carcinoma. The quality and quantity of stroma in papillae rather than the presence or absence of stromal support should also be a guiding criteria for excluding benign papillary lesions.

Tumoral calcinosis: a series of six cases with review of pathogenesis and histopathological diagnosis.

Six cases of tumoral calcinosis detected in a short period of time are reported. All the cases were in late adults and mostly in females. Most lesions were in inactive late stage. Available published literature on this rare interesting lesion has been reviewed. The etiopathogenesis and pathological features are discussed. It appears that the strict compartmentalization of lesions into different stages depending on the histological features and the importance of proliferating areas as a marker for progression and recurrence has been over emphasized.